—”Eat your fruits and vegetables” is advice handed down to us since we were children, and medical studies have backed this advice. But could some fruits and vegetables be more beneficial than others in preventing certain diseases? A new study by researchers at Brigham and Women’s Hospital (BWH) found that citrus fruits may reduce the risk of stroke in women.
The study was electronically published on February 23, 2012 in Stroke, a journal of the American Heart Association.
Kathryn M. Rexrode, MD, BWH Department of Medicine, and colleagues from the University of East Anglia, United Kingdom and the University of Bari, Italy conducted a prospective study of 69,622 women from data from the Nurses’ Health Study. Based on questionnaires participants completed during 14 years of follow-up, the researchers were able to track stroke incidence and calculate flavonoid intake. Flavonoids are a type of antioxidant found in foods such as fruits, vegetables, dark chocolate and red wine.
The researchers discovered that a particular sub-type of flavonoid called flavanone-which are abundant in citrus fruits-seemed to have a protective effect against stroke.
High consumption of citrus fruits and juices was associated with a 19 percent reduced risk of ischemic stroke (a type of stroke that happens when blood flow to the brain is blocked). Women who consumed the highest amount of flavanones had a lower risk of ischemic stroke compared to women with the lowest intake.
Participants’ main dietary sources of flavanones came from oranges and orange juice (82 percent), followed by grapefruit and grapefruit juice (14 percent).
The researchers note that in addition to flavanones, other components in citrus that may reduce stroke risk include vitamin C and potassium.
Despite the study’s praise for citrus fruits, the researchers caution that more work is still needed to confirm their findings.
“I would certainly not recommend that anyone take flavanone supplements based on this research,” said Rexrode.



